Duarte L, Alexandre M, Chaves A, Santos D, deSouza A, Bernacci L (2021) Plant-virus infection inhibitors: The great potential of Caryophyllales species. Physiol Mol Plant Pathol 113:101597. doi: 10.1016/j.pmpp.2020.101597
Summary: The proteinaceous nature of antiviral proteins (AVP) produced by Caryophyllales, as well as the role of ribosome-inactivating proteins (RIPs) and pathogenesis-related proteins (PRs) as plant-defense inducers have received considerable attention. This review proposes a model for the main mode of action hypotheses of viral infection inhibitors. The activity of two RIPs, in addition to PAP, against capped and uncapped viral RNAs has been reported. PAP, M. expansa RIP (ME1), and Saponaria officinalis RIP (saporin) depurinated capped TMV and brome mosaic virus (BMV, genus Bromovirus) RNAs, but did not depurinate uncapped luciferase RNA, indicating that in addition to PAP, other type I RIPs can distinguish between capped and uncapped RNAs.
Related Products: Saporin (Cat. #PR-01)