Author name: Kristen Hartman

Nattie EE, Li A, Richerson G, Lappi D (2002) Specific killing of rat medullary raphe 5-HT neurons by a serotonin transporter antibody-saporin conjugate reduces the ventilatory response to increased CO2 during sleep and wakefulness. Neuroscience 2002 Abstracts 221.3. Society for Neuroscience, Orlando, FL. Summary: CO2 increases the firing rate of medullary raphe 5-HT neurons in […]

Sheriff ST, Xiao C, Chance WT, Kasckow JW, Balasubramaniam A (2002) Selective lesion of neuropeptide Y (NPY)-receptor neurons in hypothalamus inhibit food intake and reduces body weight in rats. Neuroscience 2002 Abstracts 384.1. Society for Neuroscience, Orlando, FL. Summary: Administration of NPY into hypothalamic areas elicits a most powerful feeding response in rats. The neuronal

Gallegos RA, Lee RS, Crawford E, Wills DN, Carr JR, Zhukov VI, Slaght KE, Huitron-Resendiz S, Criado JR, Henriksen SJ (2002) Selective lesion of ventral tegmental area neurons expressing mu-opioid receptors alters EEG power spectrum across sleep/wake cycle. Neuroscience 2002 Abstracts 276.14. Society for Neuroscience, Orlando, FL. Summary: The ventral tegmental area (VTA) has long

Burgess SE, Gardell LR, Xie Y, Ossipov MH, Vanderah TW, Malan TP, Porreca F, Lai J (2002) Dermorphin-saporin targets descending facilitation in the rostral ventromedial medulla (rvm) to block CCK-induced abnormal pain. Neuroscience 2002 Abstracts 351.11. Society for Neuroscience, Orlando, FL. Summary: Abnormal pain from L5/L6 spinal nerve ligation (SNL) has been shown to require

Meng ID, Harasawa I, Lai J, Porreca F, Fields HL (2002) Changes in rostral ventromedial medulla (RVM) neurons after the selective loss of mu-opioid receptor expressing cells. Neuroscience 2002 Abstracts 351.9. Society for Neuroscience, Orlando, FL. Summary: Different subpopulations of RVM neurons inhibit or facilitate dorsal horn nociceptive transmission. Microinjection of saporin conjugated to the

Miller SA, Lappi DA, Wiley RG (2002) Enhanced morphine analgeisa after spinal dermorphin-saporin. Neuroscience 2002 Abstracts 218.1. Society for Neuroscience, Orlando, FL. Summary: Dermorphin-saporin (derm-sap) is a neuropeptide toxin conjugate which is selective for neurons expressing the mu-opiate receptor (MOR). The dermorphin moiety of the conjugate binds MOR which is then internalized by the neuron,

Khasabov SG, Rogers SD, Ghilardi JR, Peters CM, Mantyh PW, Simone DA (2002) Lack of capsaicin (CAP)-evoked sensitization following SP-SAP treatment is not attributed to decreased CAP-evoked exciataion. Neuroscience 2002 Abstracts 351.24. Society for Neuroscience, Orlando, FL. Summary: The depletion of SPR+ neurons in the spinal cord by substance P-saporin conjugate (SP-SAP) prevents the development

Hodges MR, Forster HV, Wenninger JM, Brozoski DT, Leekley T, Klum L, Feroah TR, Pan LG, Sengupta J (2002) Effects of lesions in the medullary raphe nucleus on sleep and breathing in adult goats. Neuroscience 2002 Abstracts 321.8. Society for Neuroscience, Orlando, FL. Summary: The medullary raphe nucleus (MRN) contains populations of both neurokinin-1 and

Forster HV, Hodges MR, Wenninger JM, Pan LG, Klum L, Leekley T, Feroah TR, Brozoski DT (2002) Breathing of awake goats after neurotoxic lesions in the medullary raphe. Neuroscience 2002 Abstracts 321.9. Society for Neuroscience, Orlando, FL. Summary: Neurokinin I immunoreactive neurons are abundantly present in the medullary raphe of adult goats. We therefore wished

Guyenet PG, Stornetta RL, Rosin DL, Wang H, Sevigny CP, Weston MC (2002) Somatostatin immunoreactivity is a diagnostic marker of the pre-Boetzinger complex. Neuroscience 2002 Abstracts 362.4. Society for Neuroscience, Orlando, FL. Summary: Selective ablation of the neurokinin-1 receptor-ir (NK1R-ir) neurons of the ventral respiratory group (VRG) causes major respiratory deficits. Since this population of