Leptin is a 16 kDa protein hormone that activates leptin receptors, and plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. Leptin inhibits the activity of neurons that contain neuropeptide Y (NPY) and agouti-related peptide (AgRP), and increases the activity of neurons expressing α-melanocyte-stimulating hormone (α-MSH), and thereby is a very influential mediator of satiety.
Leptin-SAP specifically eliminates cells that recognize and internalize leptin. It is also an excellent complement to NPY-SAP (Cat. #IT-28) and Oxytocin-SAP (Cat. #IT-46) in studying satiety, appetite, and metabolism.
To view protocol(s) for this and other products please visit: www.ATSbio.com/support/protocols