Mac-1-SAP rat Kit [KIT-33]

25 ug, 100 ug, 250 ug

a tool for eliminating cells that express Mac-1 (CD11b) receptor in rat; targeted via the antibody to CR3 (CD11b), eliminated via saporin
This kit includes Mac-1-SAP rat (Cat. #IT-33) plus Mouse IgG-SAP (Cat. #IT-18) and Mac-1 (CD11b) Mouse Monoclonal (Cat. #AB-N06)

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SKU: KIT-33 Category:

Product Description

CD11b is an alpha subunit of Mac-1, also known as CR3. CD11b is the receptor for the C3bi fragment of complement. This receptor is involved in bacterial phagocytosis. A reduction in neutrophil CD11b expression after severe traumatic injury correlates with increased septic complications. CD11b is a component of integrins, important for adhesion of neutrophils to surfaces. Mac-1-SAP recognizes the rat Mac-1 (CD11b) receptor in rat. Mac-1-SAP is excellent for removing contaminating macrophages from primary cultures to determine their role(s) in autoimmune diseases and in degenerative diseases such as Alzheimer’s.

Mac-1-SAP eliminates Mac-1-positive (CD11b-positive) cells. All other cells are left untouched.

To eliminate Mac-1-positive cells in mouse/human, use Mac-1-SAP mouse/human (Cat. #IT-06).

To view protocol(s) for this and other products please visit: www.ATSbio.com/support/protocols

View Mac-1-SAP rat Data Sheet
View Mouse IgG-SAP Data Sheet
View Mac-1 (CD11b) Mouse Monoclonal Data Sheet

View Related Mac-1-SAP rat References
View Related Mouse IgG-SAP References
View Related Mac-1 (CD11b) Mouse Monoclonal References