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Fab-pHAST: The newest targeting tool

Contributed by Patrick Shramm, Product Manager for Fab-pHast We are pleased to announce a new set of tools to rapidly screen antibodies, Fab-pHast conjugates. The ATS pHAST product line provides the FASTEST results in quantitative testing of your antibody’s specific-binding and internalization. Fab-pHast contains a pH-dependent fluorescent reporter that increases intensity in acidic surroundings, such […]

Cover Article: The locus coeruleus: a potential link between cerebrovascular and neuronal pathology in Alzheimer’s disease.

Contributed by S C Kelly, P T Nelson, S E Counts Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that most commonly affects individuals over the age of 65. While of unknown etiology, AD is characterized by a steady decline in cognitive functions including memory, attention, executive functions, and language. There is currently no disease-modifying therapy […]

Accelerating Your Research

As we start a new year, we at Advanced Targeting Systems are more dedicated than ever to providing our customers with the innovate, cutting-edge tools that will accelerate and optimize research. Scientists around the world have published exciting new data to advance our knowledge of how specific cell types affect behavior and disease. With each new discovery, possibilities […]

Targeting Trends Newsletter 16q4

Below are links to view the quarterly newsletter Targeting Trends. You can also download the full PDF here. If you would like to be added to the mailing list, please complete the information on our contact page. The latest edition of Targeting Trends, the quarterly newsletter from Advanced Targeting Systems, is now available online.  For the […]

Targeting Topics 16q4

Neural activity promotes long-distance, target-specific regeneration of adult retinal axons. Lim JH, Stafford BK, Nguyen PL, Lien BV, Wang C, Zukor K, He Z, Huberman AD. Nat Neurosci 19(8):1073-1084, 2016. PMID: 27399843 Axons in the CNS fail to regenerate after injury. Scientists sought to identify strategies that would allow retinal ganglion cell (RGC) axons to […]

New Product Manager Alena Bishop

She’s here to tell you, in her own words, what she is working on and what products to look forward to: “One of the projects I have been working on involves a novel use of specific strains of Clostridium botulinum that inhibits cells by blocking the release of neurotransmitters. This effect is long-lasting but not […]

Strategic Partners

This issue of Targeting Trends brings an exciting report of new partners that will bring more products, more expertise, and more service to our customers around the world. The primary purpose for making this change is to better facilitate the various functions that serve you, our customer. This restructure will also challenge and reward our […]

Cover Article: Targeted lesioning reveals role of nucleus incertus in the anxiogenic effect of buspirone

By Jigna Rajesh Kumar, [a, b, c, d] Ramamoorthy Rajkumar, [a, b, c] Liying Corinne Lee, [a, b, c] Gavin S. Dawe [a, b, c, d] [a] Dept Pharmacology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, 117600, Singapore [b] Neurobiology and Ageing Programme, Life Sciences Institute, National University […]

Targeting Trends Newsletter 16q3

Below are links to view the quarterly newsletter Targeting Trends. You can also download the full PDF here. If you would like to be added to the mailing list, please complete the information on our contact page. Brian Russell – Editor The latest edition of Targeting Trends is now available online. The cover article, “Targeted depletion […]