Author name: Kristen Hartman

Self-assembly of epitope-tagged proteins and antibodies for delivering biologics to antigen presenting cells

Gong S, Qiu J, Thayumanavan S (2023) Self-assembly of epitope-tagged proteins and antibodies for delivering biologics to antigen presenting cells. J Am Chem Soc doi: 10.1021/jacs.3c09334 PMID: 38147631 Objective: To describe a simple self-assembly strategy for generating artificial immune complexes. Summary: The built-in recognition domains in the antibody, viz. the Fab and Fc domains, are

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Intracellular protein delivery: Approaches, challenges, and clinical applications

Chan A, Tsourkas A (2024) Intracellular protein delivery: Approaches, challenges, and clinical applications. BME Frontiers doi: 10.34133/bmef.0035 Objective: To review progress made towards achieving cytosolic delivery of recombinant proteins and possible strategies to enable proteins to cross cell membranes. Summary: Drug delivery researchers have worked to deliver saporin into tumor cells in the hopes of

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Neuroscience

Targeting Topics /

The Advanced Targeting Systems targeting technology provides neuroscientists with the tools to identify, visualize, and or eliminate specific cell types. Some examples of scientific studies using ATS products include Learning and Memory, Circadian Rhythm, Sleeping and Wakefulness, Parkinson’s Disease, Alzheimer’s Disease, Addiction, Multiple Sclerosis, Pain Mechanisms, Eating and Diet. Learning and Memory Galanin-SAP [IT-34] PACAP-SAP

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